SOVEREIGN VANGUARD PROGRAMPHASE 1 · NOVEMBER 2026

Built here, scaled elsewhere.

What scaling friction costs Europe's deep-tech sovereignty, told through the founders, investors and institutions who were in the room.

71voices from four labs and one London finale
95%say Europe has the scientific and technological edge
16companies raised foreign capital because Europe could not supply it
14 molongest reported wait from grant application to cash
FOREWORD

Europe does not lack ideas. It lacks somewhere to grow them.

Over the autumn we sat down in Munich, Bratislava, Barcelona and Turin, and finished in London, with 71 founders, investors, researchers and officials. Almost all of them, 95%, told us that Europe has the scientific and technological edge.

Then they told us what happens next. A grant is awarded and arrives up to a year after the application. A medical device waits for certification while the cash runs out. A bigger round is not available at home, and a term sheet arrives from abroad. None of it is dramatic. Each friction is small, and together they decide where a company grows up.

That is why we call this a question of sovereignty, and why it is decided at the scale-up stage. Scaling needs the right rules, the right capital and the right customers, and a country keeps its technology only if its companies can find them at home.

This is the first of several reports. Phase 1 covers these rooms. Each phase will publish its own findings, and the full pan-European report will be presented at Lake Como in April 2027. We have tried to write plainly what we heard, to show how sure we are of each number, and to leave out names.

We hope you will read it, argue with it, and join us.

Sovereignty is not where the science is invented. It is where the companies built on it are allowed to scale.
Marcus PaletiDirector, World Technology Congress
THE STORY IN ONE PAGE

Four steps from a European lab to a company that grows somewhere else.

1

Europe has the edge

The people in the labs say Europe leads in science and deep research. US companies and a US investor say they look here for talent, research and AI governance.

95%of 71 voices
2

The edge meets friction

Certification waits drain cash. Grants take months to be decided and months more to be paid. Refusals explain nothing.

14months, longest grant wait
3

Companies grow up elsewhere

When European capital is not there, foreign capital is. Founders set up in the US, take a foreign term sheet, or sell to a buyer who relocates the company.

16raised foreign capital
4

Sovereignty is decided here

The science was funded in Europe. The jobs, the contracts and the market go where the company scales. The cost is a loss of economic value, and of control.

11founders relocating
WHO WAS IN THE ROOM · 71 COMPANIES AND INSTITUTIONS
■ 48 SMEs■ 6 scientists and professors■ 6 large enterprises■ 4 policy authorities■ 6 investor CEOs, over €5B AUM■ 1 US company
Chips and semiconductorsArtificial intelligenceBiotech and medtechQuantumSpacePrecision engineeringRoboticsDrones

Figures are reported by lab participants and are not summed where they may overlap.

CHAPTER 1 · EUROPE HAS THE EDGE

The edge is real, and the world knows it.

Ask the people in these rooms whether Europe is good at science and the answer is close to unanimous. 95% of the 71 voices said Europe has the scientific and technological edge. As one molecular biotech scientist described it, European primary research is among the most trusted anywhere.

The outsiders agree. One observer sat in every lab and brought the US perspective. The US companies and the US investor in the room said they look to Europe for talent and research, for best practice in AI governance, and to understand how civil society weighs the foreseeable risks of frontier development. On STEM and deep research, they called European universities a credible and valuable resource.

This edge is paid for by the public. A university professor reminded the room that public money funds fundamental science, so when talent and intellectual property leave, the value leaves with them.

95 of every 100 voices say Europe has the scientific and technological edge.
The same capital and regulation that are meant to enable the science become the roadblocks to growing it.The paradox, as described by a molecular biotech scientist in the labs
VOICE · ECOSYSTEM POINT[Quote, 50 words max]

Quote to come.

Ari Melnick · Josep Carreras Leukaemia Research Institute
Suggested angle: Some points mentioned in the BRC lab

Views reported by lab participants and paraphrased; the 95% is a share of the 71 voices.

THE VIEW FROM ACROSS THE ATLANTIC

The world still looks to Europe for what it knows.

One observer sat in every lab and brought the US perspective. US companies and an investor in the room said the same thing.

Europe is a credible and valuable resource for STEM and deep research.Shared view of the US companies and the US investor at the labs · Qualitative, reported by participants
1

Talent

They look to Europe for talent and for some of the best research in the world.

2

AI governance

They look to Europe for best practice in AI governance.

3

Foreseeable risk

They look to Europe to understand how civil society views the risks of frontier development.

VOICE · A US COMPANY[Quote, about 40 words]

Quote to come.

Name, title · AffirmedRx
WHY THIS MATTERS FOR SOVEREIGNTY

Europe is valued for

Research, talent, universities, governance and risk thinking

→

Europe is left short on

Scale-up capital, fast certification and grants that arrive on time

The edge is already recognised abroad. What the labs found is how often it becomes companies that grow somewhere else.

Source: the US observer present at all labs; US companies and a US investor at the labs. Views reported by participants.

CHAPTER 2 · THE EDGE MEETS FRICTION

Then the edge walks out of the door.

None of the routes we heard about involved a company giving up. Each involved a company that kept building, and found the money, the buyer or the market somewhere else.

Four routes came up again and again. They have one thing in common: the science and the intellectual property were built here, and the growth happened elsewhere.

ROUTE 1 · SET UP IN THE US
€1.1M+

A medtech founder seeking FDA approval is setting up in the US to raise and build there, then sell back into Europe, with the IP built here. The founders have already put in over €1.1M.

ROUTE 2 · A FOREIGN TERM SHEET
1 offer

A Swiss fabless chip company closed its seed and advanced seed rounds. The bigger round was not available at home, and the term sheet came from Far East investors.

ROUTE 3 · A FOREIGN ROUND
€123M

A company with European founders raised from US investors while keeping a European base. The money was there, just not in Europe.

ROUTE 4 · A FOREIGN BUYER
8+ in 3 yrs

A life-sciences hub saw at least eight companies bought by foreign investors and relocated. They had proved readiness, with clinical certification and market entry, to meet what large customers ask for.

VOICE · IP BUILT HERE[Quote, 50 words max]

Quote to come.

Jacobacci & Partners · EU IP capacity
Suggested angle: What happens to intellectual property built in Europe when the company grows abroad.

Each figure is reported by a different voice and may overlap with others, so none are added together. Companies are described by sector only.

CHAPTER 3 · CERTIFICATION AND CAPITAL

You cannot raise until you are certified. You cannot survive until you are certified.

Medical devices cannot be sold without certification, and in Europe certification runs country by country. A medtech investor, speaking for two VCs, described the trap. At least 15 of their portfolio companies were affected and at least six months were lost, in a year when they made about 60 deals and invested around €130M.

A dental AI company made it concrete. It raised €3.5M against €133M for a comparable US rival, 38 times less, while its cash drained waiting for certification. The rival is now set to enter Europe, a market the company puts at about €3B at scale. The founder supplied the figures; public information on the rival matches.

Large customers feel it too. A large pharmaceutical company told us some new SME vendors were turned down because they could not show they could scale at the speed and capital required, with certification adding to the gap. A life-sciences investor said he cannot fund companies through clinical validation, because the risk carries no reward. At least five companies have left the EU, in his experience.

THE CATCH-22
Cannot raise until certified
⇄
Cannot survive until certified

Each month of waiting uses cash the company has no way to replace.

Source: medtech investor, two VCs
CAPITAL RAISED, € MILLION
US rival133
EU dental AI company3.5
38×less capital
Source: company founder, public data
VOICE · CAPITAL[Quote, 50 words max]

Quote to come.

Pascal Joncour · Investor, Convergence Partners
Suggested angle: Why capital does not follow companies through certification, and what would change that.
ASK CARD · BARRIER

Certification country by country, with no common route

COST

At least 6 months lost; 38× less capital in one case

FIX

A certification sandbox that starts in one country and extends

WHO ACTS

Regulators and national authorities

Reported by lab participants; companies described by sector only.

CHAPTER 4 · GRANTS

Approved, but could not survive until the money arrived.

Grants are meant to carry a young company through its riskiest years. We heard from a funding-programme observer with feedback from at least 120 SMEs since 2022. An application takes three to four months. A decision takes another three to four. Refusals come with no useful feedback.

Winning is not the end of the wait. In about 30% of awarded grants, the money arrived up to six months later still. From application to cash, that is up to 12 to 14 months. For a company burning cash, that is the difference between a grant and a lifeline that comes too late.

The design matters as much as the timing. Several founders said grants reward a research project more than a commercial business, and change the founder's mindset. A hardware founder in Germany said national grants are spread across regions instead of awarded on merit, costing business and talent. A university venture builder, supporting about four start-ups a week, said grant rules can stop a company building with its own money until the grant arrives.

FROM APPLICATION TO CASH, MONTHS (UPPER BOUNDS)
Application (3–4)
Decision (3–4)
Payment (up to 6 more)
02468101214
30%of awarded grants were paid late
Each dot is 1 in 100 awarded grants; 30 are late. Source: funding-programme observer
ASK CARD · BARRIER

Late payment and refusals that explain nothing

COST

Up to 14 months from application to cash

FIX

Pay within a fixed number of days; a bridge facility; real feedback on refusals

WHO ACTS

Grant-awarding bodies

Reported by lab participants; timings are upper bounds.

CHAPTER 5 · TALENT AND THE REWARD FOR RISK

Europe trains the talent. Others hire it.

Three companies, in space and precision engineering, biotech and chip raw materials, told us they have ten key positions open between them. The space company also struggles to source raw materials locally.

The companies said they look first to Europe for this talent, and Europe is rich in it. Yet it grows scarce here, absorbed by opportunities elsewhere. A US investor at a different lab agreed.

A fabless chip company described the squeeze: big companies absorb scarce skills, so scale-ups turn to India and outsource roles. The jobs a European scale-up would have created are created elsewhere.

Behind talent sits reward. A frontier-tech advisor said founders, investors and government all take less risk on frontier industries in Europe. A space founder who built and sold a company in the US, then returned to build satellites, said the EU lacks rewards proportional to investor risk. By his estimate, the sector could add €6 to 8B in revenue and his company could build 200 satellites a year.

KEY POSITIONS OPEN ACROSS THREE COMPANIES
10roles unfilled
  • 1 extraterrestrial metallurgy engineer
  • 2 design verification engineers
  • 1 computational biologist
  • Several cell and gene therapy process development engineers and clinical automation specialists
  • 3 tool development specialists for microchips
Source: three companies, first-hand
WHERE THE TALENT GOES
  • Larger companies, which absorb scarce skills
  • US regions, which pay more
  • India, for scale-ups outsourcing roles
Source: space company; fabless chip company
VOICE · UNIVERSITIES AND TALENT[Quote, 50 words max]

Quote to come.

A university's venture lab
Suggested angle: How a university builds companies and keeps talent and IP in Europe as they scale.
ASK CARD · BARRIER

Scarce skills pulled to larger employers and higher-paying regions

COST

10 key roles open across three companies

FIX

To be shaped with the labs: proposals welcome

WHO ACTS

Employers, universities and governments

Reported by lab participants; the €6 to 8B and 200 satellites are one founder's own estimates.

WHAT THE FRICTION COSTS

Every number, graded by how far we can stand behind it.

The labs produced figures of different quality. Rather than add them into one headline total, we show each at its true weight. Read from the top: the higher the rung, the firmer the ground.

Show:
AFirst-hand, measured
38×less capital for an EU medtech than its US rival
€123Mraised from US investors by a company with European founders
€1.1M+already put in by founders setting up in the US
10key positions open across three companies
BFirst-hand estimate
6+ molost to certification across at least 15 portfolio companies
to 14 mofrom grant application to cash; 30% of awards paid late
8+ in 3 yrscompanies bought and relocated abroad, one hub’s count
5+large-enterprise contracts lost across three companies
COpinion, second-hand

Founders, investors and governments take less risk on frontier industries.

Grants are spread across regions instead of awarded on merit.

Public money funds science, then the value leaves with the talent and IP.

VOICE · THE ECONOMICS[Quote, 50 words max]

Quote to come.

Dario Peirone · Director General, Milton Friedman Institute
Suggested angle: What it costs an economy when its best companies scale elsewhere, and why sovereignty is an economic question.

Basis grades follow the Phase 1 evidence table. Figures are reported by lab participants.

WHAT HAPPENS NEXT

This is the first chapter. The next labs are coming to a city near you.

Each phase publishes its own findings. By Lake Como in April 2027, the full pan-European report will bring them together: an estimated 300 SMEs in frontier sectors, at least 50 investors, and many institutions and governments.

PHASE 1 · AUTUMN 2026This report
PHASE 2 · EARLY 2027Eight more stretches of labs
LAKE COMO · APRIL 2027The full pan-European report
THE NEXT LABS · EARLY 2027 · 22 CITIES
1

Danube corridor

Prague, Vienna, Budapest

2

Adriatic

Zagreb, Ljubljana

3

Alps–Paris

Grenoble, Paris-Saclay

4

Poland–Baltics

Warsaw, Vilnius, Riga

5

Nordic–Baltic

Tallinn, Helsinki, Stockholm, Copenhagen

6

South-East

Bucharest, Sofia, Athens

7

Benelux

Eindhoven, Leuven, Luxembourg

8

Atlantic

Lisbon, Porto

Dates for each lab will be shared with those who register interest.

SMEs, INVESTORS, INSTITUTIONS

If you build, fund or govern in a frontier sector, there is a seat for you at a lab near you. Early notice lets you apply to be in the room.

Register interest
E6 CONCORD · LAKE COMO · 28–30 APRIL 2027

Where the findings meet the people who can act.

100 SMEs, investors and institutions. Free seats. Apply by 12 February 2027; confirmations by 5 March.

Apply for a seat

Participation figures are targets.

ACKNOWLEDGEMENTS

Thank you.

To the 71 voices in Munich, Bratislava, Barcelona, Turin and London who told us the truth: this report is yours.

OWNED BY
WITH THE SUPPORT OF
WITH THANKS TO
NEXT: LAKE COMO, 28–30 APRIL 2027

The full pan-European report will be presented at E6 Concord.

Apply for a seat

Listing supporters does not imply endorsement of the findings. Photographs used with participants' consent.

An independent initiative of the World Technology Congress. The EIB has not organised, commissioned, sponsored or approved the programme or this report.